Can CBD help treat brain cancer?
British researchers have highlighted the action of CBD on different types of cancer. Cannabidiol seems to hold significant potential for treating brain cancer, which now needs to be explored.
CBD has an impact on the treatment of brain cancer.
This study was conducted by the School of Human Sciences at London Metropolitan University in the United Kingdom and its team of scientists. Published on December 28, 2018, it focused on a particular and very serious type of brain cancer: Glioblastoma Multiforme (GBM).
Particularly dreaded, glioblastoma multiforme (GBM) is the most common form of malignant primary brain tumor in adults. While numerous studies have been conducted on it, Professor Pierre-Yves Deprez's (California Pacific Medical Center, San Francisco) research is of particular interest. He demonstrated that CBD, under certain circumstances, has a positive effect on GBM treatment.
Researchers at London Metropolitan University likely consulted this study when beginning their own.
CBD has proven efficacy as an adjunct to current treatments.
When studying its impact, British researchers focused on CBD's action in the proliferation of cancer cells. It is broken down into two parts: extracellular vesicles (EVs), essential for the transfer of proteins, genetic material, and useful for the movement of cancer cells; and prohibitin, an agent that can contribute to the resistance of cancer cells to chemotherapeutic agents.
Conclusion: extracellular vesicle (EV) inhibitors increase the sensitivity of cancer cells to chemotherapy, and cannabidiol (CBD) acts as a modulator of the latter. It was then necessary to ascertain the effect of CBD on the EV profile in cancer cells in the presence and absence of temozolomide, which helped consolidate the hypothesis of an active role.
In both cases, during CBD treatment, the impact was positive: extracellular vesicles were multiplied and more robust, while prohibitin was reduced. Consequently, the authors consider that "CBD can play a complementary role in improving the effectiveness of GBM treatment."
